*Bucknell students
Switzer, R. L., Hartman, Z. J.*, Hewett, G. R.*, and Carroll, C. F.* (2023) “Disease-Associated Mutation A554V Disrupts Normal Autoinhibition of DNMT1” DNA 3, 119-133. DOI: 10.3390/dna3030010
Switzer, R. L., Ward, K. A.*, and Medrano, J.* (2022) “Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors” J. Vis. Exp. (186), e62949. DOI: 10.3791/62949
Palfey, B. A. and Switzer, R. L. (2022) Kinetics of Enzyme Catalysis; American Chemical Society. DOI: 10.1021/acsinfocus.7e5015
Dolen, E. K.*, McGinnis, J. H.*, Tavory, R. N.*, Weiss, J. A.*, and Switzer, R. L. (2019) “Disease-associated mutations G589A and V590F relieve RFTS-mediated autoinhibition of DNA methyltransferase 1” Biochemistry 58, 5151-5159. DOI: 10.1021/acs.biochem.9b00749 ACS articles on request link
Switzer, R. L., Medrano, J.*, Reedel, D. A.*, and Weiss, J.* (2019) “Substituted anthraquinones represent a potential scaffold for DNA methyltransferase 1-specific inhibitors” PLoS ONE 14, e0219830. pone.0219830
Huang, J., Stewart, A., Maity, B., Hagen, J., Fagan, R. L., Yang, J., Quelle, D. E., Brenner, C., and Fisher, R. A. (2014) “RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis” Oncogene 33, 3604-3611. nihms-633989
Fagan, R. L., Wu, M., Chedin, F. and Brenner, C. (2013) “An ultrasensitive high throughput screen for DNA methyltransferase-targeted molecular probes” PLoS One 8, e78752. pone.0078752
Fagan, R. L., Cryderman, D. E., Kopelovich, L., Wallrath, L. L. and Brenner, C (2013) “Laccaic acid A is a direct, DNA-competitive inhibitor of DNA Methyltransferase 1” J. Biol. Chem. 288, 23858 – 23867. jbc23858
Syeda, F., Fagan, R. L., Wean, M., Avvakumov, G. V., Walker, J. R., Xue, S., Dhe-Pagano, S. and Brenner, C. (2011) “The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1” J. Biol. Chem. 286, 15344 – 15351. jbc15344
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